Know what’s inside:
In vitro & in vivo Pharmacology
In-depth knowledge
To gain profound and relevant preclinical data on efficacy and potency, in-depth knowledge of the corresponding disease is a key success factor.
The GBA Group has a proven track record on conducting In vitro and in vivo studies on potency, selectivity and efficacy in several indication areas.
Ihr direkter Kontakt
Dr. Daniel Da Costa
BD Director Preclinical Services Europe
In vitro Pharmacology Assays
5α Reductase Inhibitors
- Human Recombinant Isoenzymes Type I and II
In vivo Pharmacology Models
Diabetes / Metabolic Syndrome Models
- Induced Models:
- STZ Mice/Rats
- DIO Mice/Rat
- Genetic Models
- ob / ob Mice
- db / db Mice
- Zucker /ZDF Rat
Cancer
- In vivo Model
- (immunodeficient mice)
- Principle:
- s.c. tumor xenograft model
- General Readouts:
- Tumor incidence, tumor size, tumor growth inhibition, terminal tumor weight, occurrence of metastases (Postmortal)
