Know what’s inside:
In vitro & in vivo Pharmacology
In-depth knowledge
To gain profound and relevant preclinical data on efficacy and potency, in-depth knowledge of the corresponding disease is a key success factor.
The GBA Group has a proven track record on conducting In vitro and in vivo studies on potency, selectivity and efficacy in several indication areas.
Your direct contact
MUDr. Maria Li
Director Business Development
Mobile: +49 173 889 4288
Mail: m.li@gba-pharma.com
In vitro Pharmacology Assays
5α Reductase Inhibitors
- Human Recombinant Isoenzymes Type I and II
In vivo Pharmacology Models
Diabetes / Metabolic Syndrome Models
- Induced Models:
- STZ Mice/Rats
- DIO Mice/Rat
- Genetic Models
- ob / ob Mice
- db / db Mice
- Zucker /ZDF Rat
Cancer
- In vivo Model
- (immunodeficient mice)
- Principle:
- s.c. tumor xenograft model
- General Readouts:
- Tumor incidence, tumor size, tumor growth inhibition, terminal tumor weight, occurrence of metastases (Postmortal)