Know what´s inside:

Analytical Services (Agrochemicals - Chemicals - Pharma)

Your partner for agrochemical analysis

Pharmacelsus is a GLP certified test facility supporting regulated analytical services in the field of toxicology, ecotoxicology and agricultural chemistry.

Our portfolio encompasses analytical method development for small and large molecules as well as bio-macromolecules. For analytical validation procedures and sample analysis the current regulatory guidances for chemical-, pharmaceutical- and crop protection industries are applied.

We use state of the art LC-MS instrumentation with high resolutions of up to 280,000 enabling us to selectively and sensitively quantify your compound of interest. The detection limits reach down to 10 picogram per milliliter within solid and liquid biological or non-biological matrices.

The identification of metabolites, degradation products or contaminants complete our services.

Our Services

Analytical method validation and sample analysis

for chemicals, drugs and crop protection products
in biological or non-biological matrices (solid and liquid)
LC-MS and LC-MS/MS analysis applying high resolution mass spectrometry

Concentration control for GLP ecotoxicological studies

for OECD test 210 ELS (zebrafish)
for OECD test 211 daphnia
for OECD test 221 lemna
for OECD test 201 algae
other tests upon request

Analysis of toxicokinetic samples

animal and human body fluids
animal and human tissues
calculation of toxicokinetic parameters
analysis of residues

Specialized analytical support for chemical or crop protection products

Analysis of in vitro assays
Liver enzyme inhibition and -induction assays

Determination of metabolites, degradation products and contaminants

software supported search of new metabolites
identification of degradation products
database search and identification of contaminants or residues

Concentration analysis

in chemical intermediates and products
in crop products or -formulations
in drug formulations

Regulatory- and industrial guidances involved

OECD Guidelines for the Testing of Chemicals
OECD guidance documents for GLP and compliance monitoring
Guidelines on bioanalytical method validation: ICH M10 (from 2023)
SANTE/11312/2021: Analytical quality control and method validation procedures for pesticide residues analysis in food and feed