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A wide range of byproducts arise from synthesis reactions

During the production of active substances as well as finished products in pharmaceutical biotechnology, a wide range of byproducts arise from synthesis reactions. Trace elements, such as detergents or genotoxic compounds are also present in biotechnological fermentation solutions. 

In the context of a down-stream process, these byproducts must be depleted in a multi-step process. 

GBA Pharma Labs have developed and validated analytical methods for a wide range of these compounds in diverse matrices (e.g. high protein-concentrations), which have yielded high quality depletion processes for our customers. 

That includes, among others:

  • Polysorbates
  • Poloxamers
  • Triton X
  • Dextran
  • PEG
  • Sugar
  • Methotrexate
  • Simethicone
  • Geneticin
  • Aureomycin
  • Hygromycin
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