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Coronavirus Update March - LKF

Updates regarding the current Covid-19 situation:

Please find latest news down below.

In the light of the dynamic circumstances around the Coronavirus, LKF would like to reassure you that we are constantly monitoring the situation with the goal of maintaining uninterrupted shipments of our supplies to your clinical sites as well as biological specimens to LKF, while also protecting the health of our employees. Although some countries have closed their borders the merchandise traffic is mainly still possible. The situation changes on a daily basis and there is no guarantee that the status that may apply today will apply the next days as well. We will try to keep you updated as soon as possible. In case of any questions please contact the project team via email or phone.

30.03.2020

According to DHL there is a restrictions for the DHL Express Service to South Africa. An exception for the restrictions is a transport for necessary transport. Therefore LKF will still be able to ship to/from South Africa.

World Courier informed us that they are maintaining their supply chain. They use the best available transport and storage options even in case of new border restrictions an limited airfreight availability, resctriced movement and an evolving situation. They are also facing restrictions for South Africa but maintaining the import and export.

27.03.2020

Marken informed us that they are able to provide alternate routes in most of the critical areas. The transit time may have a delay due to the circumstances. Marken is still not able to provide a service in Georgia as this country has a country-wide lockdown. DHL has a delay for shipments from/to Georgia as well. Please allow more time for a shipment to/from LKF in generell as there are time delays for most shipments.

However, most updates are still valid and LKF is able to operate normally.

For more details:World Courier/DHL/FedEx/TNT

https://www.worldcourier.com/insights/world-courier-update-covid19

https://www.dhl.de/de/geschaeftskunden/express/coronavirus.html

https://www.fedex.com/en-us/service- alerts.

htmlhttps://www.tnt.com/express/en_gb/site/home.html

26.03.2020

Quite a few countries have closed borders or even a country lockdown. Mostly the travel of goods is not affected. If you are not sure about a certian county please contact LKF. Please find an overview here.

25.03.2020

Most of our couriers are not insisting of a signature for a delivery of a package anymore.

World Courier:

They are providing contact-free pick-up and delivery of all shipments. World courier will contact the shipper or consignee by telephone in advance to confirm the recent situation in place regarding the COVID-19 situation.

FedEx:

FedEx is only seeking for a verbal confirmation and there is no need for a signature upon delivery. As all non essential shops and services are closed in ost of the European countries there is no delivery to a destination or business that is closed.

DHL:

DHL is also not insiting on a signature upon delivery. The recepient will make a signature on their own paper which will be pictured by a DHL employee.

LKF generelly is able to operate a normal business overall. There may be restrictions for shipments with the couriers for certain areas. If you require assistance for a special shipment please contact LKF directly. We will get in contact with the couriers and provide further information. LKF is supplying re-supplies as soon as possible. Hewever there might be a delay of transit for the shipments of goods as well.

24.03.2020

For a generell overview please follow here

Latest courier updates:

Marken:

"Marken and UPS are fully operational. Where commercial flights are not available, Marken utilizes the UPS network. Where necessary, we leverage other ground and air transportation options." A detailed list will be shown in the chart.

Currently mentioned critical countries: Moldova, Georgia, Lebanon: under lockdown, no Import/ Export possible

Ukraine, Poland, Romania, Finland, Denmark, Bulgaria, Croatia: closed borders, Export with UPS still possible.

DHL:

There are temporary service adjustments for several countries worldwide. A shipment will cause additional transit time. Please refer to the DHL website to get the details of the delays for all countrys in working days. https://www.dhl.de/de/geschaeftskunden/express/coronavirus.html

A service within the EU is possible but the delivery may be delayed due to local restrictions. Currently the following countrys have a limitation of service or no service available: Bulgaria (Bansko), France, Greenland (whole country), Italy (Bologna), Austria, Portugal, Spain, Czech Republic, Turkey, China (Wuhan), India, MENA, Nepal

FedEx/TNT

Currently LKF is shipping all lab supplies to the US in cooperation with FedEx.

FedEx is running normal operations as far as the local restrictions allow. For detailed information visit:

https://www.fedex.com/en-us/service- alerts.

htmlhttps://www.tnt.com/express/en_gb/site/home.html

The cargo flights are not affected by the 30 day European travel ban. FedEx has increased their flights from Europe to the U.S. in order to guarantee the delivery of goods. At the moment LKF is only affected with a delayed transit time of shipments to the USA and Canada.

Special Express:

Without any problems so far: Germany, Denmark, Great Britain, Netherlands, France, Switzerland, Austria, Czech Republic, Slovakia, Hungary, Croatia, Slovenia, USA, Canada

Delivery with delay:Italy, Spain, Portugal, Baltic States, Romania, Bulgaria, Poland, Georgia, Finland, Sweden, Norway

23.03.2020

Depending on the country and the courier there might be restrictions of transportation for goods. Though, we are still able to ship most of the samples from/to all critical areas. A delay of the transit and additional charge for some transports may be possible. Please find an overview here for all countries (LKF is working with) regarding the possible shipments with our couriers (an explanation for the colour coding is stated at the end of the chart).

20.03.2020

Due to border closures or country lockdowns LKF is also facing some difficulties for shipments to certain countries.

The shipment of certain areas can be restricted dependig on the courier and the area of destination. Please see an overview of all countries LKF is cooperating with here.

However, we are still able to work with our special couriers and therefore we can still provide a service to most countries. Additional fees can apply. If you do have any questions please get back to us.

Currently there is also enough material on stock at LKF to ship all requested re-supplies to the trial sites. We received feedback from our suppliers that they are working with high power to keep up the supply chain. There might be a delay for certain articels depending on the country of manufacturing. LKF is making all efforts to avoid any problems regarding the shipments done for our clinical trials. In case of supply difficulties we are also looking for alternative articels in order to guarantee the supply chain for the sites. As of the state right now the supply of sanitary products may be delayed but LKF still has articels on stock.

In regard of the current situation please order needed materials ahead of time.

19.03.2020

The movement of goods is still taking place without limitation from/ to Germany eventhough there are border controls. Currently travellers have restricted access to cross the borders but the border controls are not affecting the supply chain for LKF so far. Limitations or delays of shipments may occur depending on the courier.

LKF is working on high demand to ship all requested supplies as soon as possible and within a short period of time to guarantee a re-stock for all clinical trial sites. LKF may request a confirmation for certain shipments of samples. However, we are still performing the usual business. Updates for shipments with DHL:

There are no essentiell limitations of service within Germany.

Currently it is prohibited to export any medical protective gear out of Germany.

The service provided by DHL Express is still possible within the EU. Due to local restrictions delays are possible. Additionally some shipments in areas with closed public facilities and shopping centers may not be able to be served.

Currently the following countires have a limitation of service or no service availabe: Bulgaria (Bansko), France, Greenland (whole country), Italy, Austria, Portugal, Spain, Czech Republic, Turkey

DHL Express is able to ship to and from China. No service to Guinea-Bissau, Libya, Somalia. Limited service or delays: Iran, Iraq, Jordan, Djibouti, La Reunion, Sudan, Somaliland.

For all other international shipments there may be a delay of delivery due to border controls, cancelled flights or problems of delivery at the destination.

Link to get to the DHL website: https://www.dhl.de/de/geschaeftskunden/express.html#coronavirus

Marken

Currently mentioned critical countries: Moldova, Georgia, Lebanon: under lockdown, no Import/ Export possible

Ukraine, Poland, Romania, Finland, Denmark: closed borders, Export through the work with UPS still possible.

New Updates:

USA: closing of the border with Canada for non-essential trafficCanada: reduction of international flightsFrance: increased restrictions, Marken continues to make collections and deliveriesItaly: further restrictions aplly, cancellations may occurSpain:closed bordersIndia: further restrictions, no delays in shipments reported so farUnited Kingdom: reduced and cancelles flights, normal business operationPhilippines: Luzon as quarantine zoneSouth Korea: impacted flight schedules, Imports and Exports still possibleChina: New Import restrictions

The European Union banned all travelers from outside the EU for 30 days.

18.03.2020

Due to the closed borders for foreigners into the US, LKF will use Fedex for all shipments related to the USA. As Fedex is only employing american pilots they are not affected by the closing of the borders. LKF can therefore guarantee the supply chain from/ to the US.

We also created a Business Continuity Plan for an outbreak of infectious diseases. World Courier is keeping us updated about their possibilities regarding the transportation:

Due to the corona outbreak multiple airlines are reducing their flights nationwide. Delays or closures are affected for the following nations: China, Hong Kong, Israel, Japan, Mongolia, Saudi Arabia, Serbia, Singapore, South Korea, Spain, Ukraine, UK and Ireland, Norway, Denmark, Poland, Slovakia, Philippines, Italy, Czech Republic, Peru, Germany, Croatia, Hungary, Romania, Slovenia, Taiwan, Russia, Austria, Ecuador, Malta, Brazil, Chile, Cyprus, Greece, Macedonia, Belgium, Estonia, Finland, Latvia, Mexico, Moldova, and Oman.

All couriers are working on high demand to ship all supplies and samples to the designated destination. As there are some limiations some shipments may be delayed or cause extra costs as they need to be re-scheduled.

If you do need any re-supply please inform our project team in order for us to prepare your requested supply. We are operationg and shipping supplies and samples as usual.

17.03.2020

Shipments from and to LKF with SPE:

Without any problems so far: Germany, Denmark, Great Britain, Netherlands, France, Switzerland, Austria, Czech Republic, Slovakia, Hungary, Croatia, Slovenia, USA, Canada

Delivery with delay:Italy, Spain, Portugal, Baltic States, Romania, Bulgaria, Poland, Georgia, Finland, Sweden, Norway

Please also find a chart with all countries LKF is cooperating to/from:

Country status

Although quite a few countries have already cancelled a broad range of their flights, the courier services are still able to provide alternative routes for most countries. There might be a delay for some shipments.

16.03.2020

The situation changes on a daily basis. We will try to keep you updated as soon as possible.

In the light of the dynamic circumstances around the Coronavirus, LKF would like to reassure you that we are constantly monitoring the situation with the goal of maintaining uninterrupted shipments of our supplies to your clinical sites as well as biological specimens to LKF, while also protecting the health of our employees.

Currently all borders to Germany are closed for the transit of all tourists. The merchandise traffic is not affected at the moment. Nevertheless it can cause delays in the delivery of supplies for the sites and samples to LKF. Additionally some countries have closed their borders for flights. Our logistics team is working on high demand to re-schedule the routes and to guarantee the ongoing delivery of all goods and samples.

Currently it is not possible to get any samples from or to Italy, which is why scheduled pick-up dates had to be postponed.

At the current situation LKF is able to continue the manufacturing and distribution of all lab supplies. Also laboratory analysis is not affected and we are maintaining normal business operations. Due to the fact that we have no influence on the collection process of biological specimens, we keep the main focus on logistic and analysis.

We also prepared a pandemic plan and we will be able to work according to that plan if situation is worsening.

Marken's DAILY COVID-19 CRITICAL SUPPLY CHAIN UPDATES March 16 2020

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